Agomelatine Impurity 49 CAS CATO-C4X-110849
| CAS No. | CATO-C4X-110849 |
| Molecular Formula | C13H13NO |
| Molecular Weight | 199.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Agomelatine Impurity 49 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Agomelatine Impurity 49 (CAS CATO-C4X-110849, C13H13NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Agomelatine Impurity 49 (C13H13NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Agomelatine Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13NO |
| Molecular Weight | 199.25 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Agomelatine Standards
- Agomelatine Impurity 23 (CAS 178676-65-8)
- Agomelatine Impurity 36 (CAS 127299-26-7)
- Agomelatine Impurity 41 (CAS 2243666-95-5)
- Agomelatine Impurity N10 (CAS 861960-34-1)
- Agomelatine Impurity 13 (CAS 138113-09-4)
- Agomelatine Impurity 15 (CAS 138113-08-3)
- Agomelatine Impurity 37 (CAS 72836-71-6)
- Agomelatine Impurity 27 (CAS CATO-C4X-110827)
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