Cabazitaxel Impurity 50 (4R) CAS CATO-C4X-111550
| CAS No. | CATO-C4X-111550 |
| Molecular Formula | C45H57NO14 |
| Molecular Weight | 835.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Cabazitaxel Impurity 50 (4R) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Cabazitaxel Impurity 50 (4R) (CAS CATO-C4X-111550, C45H57NO14) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Cabazitaxel Impurity 50 (4R) (C45H57NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 835.93 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C45H57NO14 |
| Molecular Weight | 835.93 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Cabazitaxel Standards
- Cabazitaxel (CAS 183133-96-2)
- Cabazitaxel Impurity 16 (CAS CATO-C4X-111516)
- Cabazitaxel Impurity 18 (CAS 1714967-27-7)
- Cabazitaxel Impurity 35 (CAS CATO-C4X-111535)
- Cabazitaxel Impurity 36 (CAS CATO-C4X-111536)
- Cabazitaxel-d6 (CAS 1383561-29-2)
- Cabazitaxel-d9 (CAS 1383572-19-7)
- Cabazitaxel Impurity 10 (CAS CATO-C4X-111510)
Recommended Standards
- 1,1,2,2-Tetrakis(4-iodophenyl)ethene (CAS 299914-63-9)
- 22:6 PE (CAS 123284-81-1)
- 2-(Bis(3,5-di-tert-butylphenyl)phosphino)-N-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)benzamide (CAS 2389028-68-4)
- 1,1,2,2-Tetrakis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethene (CAS 1660996-72-4)
- Topiramate Impurity 17 (CAS 97240-80-7)
- Iguratimod Impurity 47 (CAS 149456-97-3)
- Limaprost Impurity 8 (CAS CATO-C4X-21458)
- 1-(Tert-butyl) 2-methyl (2R,4R)-4-(fluoromethyl)pyrrolidine-1,2-dicarboxylate (CAS 2306246-83-1)
- 6-chloro-4-nitro-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-Pyrrolo[2,3-b]pyridine (CAS 869335-22-8)
- Thioctic Acid Impurity 52 (CAS CATO-C4X-152652)
- 9,10,10-Trioxo-9h-10lambda6-thioxanthene-3-carboxamide (CAS 51762-93-7)
- Dibutyl Itaconate (CAS 2155-60-4)
- 1-(2,2,2-Trifluoroethyl)cyclopropan-1-ol (CAS 1078627-29-8)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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