Sildenafil Impurity 277 CAS CATO-C4X-1128277
| CAS No. | CATO-C4X-1128277 |
| Molecular Formula | C27H36N6O5 |
| Molecular Weight | 524.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Sildenafil Impurity 277 (CAS CATO-C4X-1128277) is a certified pharmaceutical impurity reference standard with the molecular formula C27H36N6O5 and a molecular weight of 524.61 g/mol.
The molecular framework of Sildenafil Impurity 277 (C27H36N6O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Sildenafil Impurity 277 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H36N6O5 |
| Molecular Weight | 524.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Sildenafil Standards
- Sildenafil Impurity 262 (CAS CATO-C4X-1128262)
- Sildenafil Impurity 75 (CAS 2253964-66-6)
- Sildenafil Impurity 33 (CAS CATO-C4X-112833)
- Sildenafil Impurity 258 (CAS 1007310-62-4)
- Sildenafil Impurity 304 (CAS CATO-C4X-1128304)
- Sildenafil Impurity 78 (CAS CATO-C4X-112878)
- Sildenafil impurity 249 (CAS CATO-C4X-1128249)
- Sildenafil Impurity 252 (CAS CATO-C4X-1128252)
Recommended Standards
- Formoterol Impurity N1 (CAS 43229-66-9)
- Amoxicillin Impurity 38 (CAS CATO-C4X-114838)
- 2,2'-((9H-Fluorene-2,7-disulfonyl)bis(azanediyl))bis(3-methylbutanoic acid) (CAS 307941-68-0)
- Emtricitabine Impurity 3 (CAS 2331211-44-8)
- Cinitapride impurity 9 (CAS 86718-17-4)
- Docetaxel Impurity 16 (CAS 161759-90-6)
- Tolvaptan Impurity 35 (CAS CATO-C4X-195535)
- 4-(3-Fluorophenyl)-2-(pyrrolidin-2-yl)-1H-imidazole (CAS 1153105-20-4)
- 5-Hydroxy-2H-thiopyran-3(6H)-one (CAS 61363-71-1)
- N10-Monodesmethyl N10-Benzyl Rizatriptan (CAS 144035-41-6)
- Cyproheptadine-d3 (CAS 2712455-05-3)
- Uridine Impurity 20 (CAS CATO-C4X-233420)
- 1-(tert-Butyl)-1H-pyrazol-4-yl dimethylcarbamate (CAS 88558-98-9)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com