Arbidol Impurity 20 CAS CATO-C4X-112920
| CAS No. | CATO-C4X-112920 |
| Molecular Formula | C18H22Br2N2O4 |
| Molecular Weight | 490.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Arbidol Impurity 20 (CAS CATO-C4X-112920, C18H22Br2N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Arbidol Impurity 20 (C18H22Br2N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H22Br2N2O4 |
| Molecular Weight | 490.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Arbidol Standards
Recommended Standards
- 4,7-Bis(4-bromophenyl)-1,10-phenanthroline (CAS 97802-08-9)
- N1,N3-bis(2,4-dichlorophenyl)-2-(((2-(dimethylamino)ethyl)amino)methylene)malonamide (CAS 339276-41-4)
- 3,3'-Dibromo-9,9'-bicarbazole (CAS 2237969-71-8)
- 1,2-Di(4-bromophenyl)-1,2-diphenylethylene (CAS 184239-35-8)
- Nalmefene Impurity N5 (CAS 91598-83-3)
- Dextromethorphan Impurity 32 (CAS 51072-36-7)
- Abiraterone Impurity 19 (CAS 2484719-16-4)
- 3-Nitro-4,5-dihydro-1,2-oxazole (CAS 1121-14-8)
- N-(4-Methoxyphenyl)-3-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide (CAS 1956386-25-6)
- 2-Phenoxyethyl-1，1，2，2-d4 Alcohol (CAS 1219804-65-5)
- 3-(3,3-Dimethylbutoxy)-2,2-dimethylpropane-1-sulfonyl chloride (CAS 1493952-48-9)
- 2-Chloro-4-(1-fluoroethyl)pyridine (CAS 1307255-24-8)
- 5-Bromobenzo[b]thiophene-2-carboxamide (CAS 38313-93-8)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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