(3RS.5SR)-Atorvastatin EP Impurity B (Calcium Salt) CAS CATO-C4X-1132113
| CAS No. | CATO-C4X-1132113 |
| Molecular Formula | C33H34FN2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(3RS.5SR)-Atorvastatin EP Impurity B (Calcium Salt) (CAS CATO-C4X-1132113) is a certified pharmaceutical impurity reference standard with the molecular formula C33H34FN2O50.Ca and a molecular weight of 1317.67 g/mol.
The molecular framework of (3RS.5SR)-Atorvastatin EP Impurity B (Calcium Salt) (C33H34FN2O50.Ca) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C33H34FN2O5 0.5*Ca |
| Molecular Weight | 597.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >50% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
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