Lenvatinib Impurity 77 CAS CATO-C4X-114077
| CAS No. | CATO-C4X-114077 |
| Molecular Formula | C12H11NO4 |
| Molecular Weight | 233.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lenvatinib Impurity 77 (C12H11NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Lenvatinib Impurity 77 (CAS CATO-C4X-114077), a pharmacopoeial impurity reference standard (molecular formula C12H11NO4, MW 233.22 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11NO4 |
| Molecular Weight | 233.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Lenvatinib Standards
- Lenvatinib Impurity 149 (CAS CATO-C4X-1140149)
- Lenvatinib Impurity 17 (CAS 205448-65-3)
- Lenvatinib Impurity 81 (CAS CATO-C4X-114081)
- Lenvatinib Impurity 36 (CAS 6657-04-1)
- Lenvatinib Impurity 60 (CAS CATO-C4X-114060)
- Lenvatinib impurity 166 (CAS CATO-C4X-1140166)
- Lenvatinib Impurity 136 (CAS CATO-C4X-1140136)
- Lenvatinib Impurity 147 (CAS 863786-02-1)
Recommended Standards
- Levosimendan impurity 77 (CAS CATO-C4X-130877)
- Tadalafil Impurity 113 (CAS 68807-89-6)
- Cefprozil EP Impurity C(Cefadroxil EP Impurity E) (CAS 147103-93-3)
- 933940-12-6 5-Amino-3-(2-methoxyphenyl)isoxazole-4-carboxamide MFCD15146466 (CAS 933940-12-6)
- Dexrazoxane Impurity 6 (CAS CATO-C4X-20206)
- Perospirone Impurity 54 (CAS CATO-C4X-245854)
- Nifedipine Impurity 35 (CAS CATO-C4X-141035)
- 2-Bromo-5-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine (CAS 638352-42-8)
- 3-(4-Ethylphenyl)-6-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1713588-30-7)
- 7,8-Dimethyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-2-carboxylic acid (CAS 63768-47-8)
- 5-(4-Bromophenyl)-2-methylpyrimidine (CAS 131548-21-5)
- 4-[4-Methyl-5-(1H-pyrazol-3-yl)-1,3-thiazol-2-yl]pyridine (CAS 499796-06-4)
- 3-(Aminomethyl)-5-nitrophenol (CAS 1261852-63-4)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com