Alvimopan impurity 18 CAS CATO-C4X-114518
| CAS No. | CATO-C4X-114518 |
| Molecular Formula | C27H27NO6S |
| Molecular Weight | 493.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Alvimopan impurity 18 (CAS CATO-C4X-114518), a pharmacopoeial impurity reference standard (molecular formula C27H27NO6S, MW 493.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Alvimopan impurity 18 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 493.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Alvimopan impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H27NO6S |
| Molecular Weight | 493.57 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Alvimopan Standards
- Alvimopan Impurity 5 (CAS 660848-91-9)
- Alvimopan-D5 (CAS 1217616-62-0)
- Alvimopan (CAS 156053-89-3)
- Alvimopan Impurity 6 (CAS 156130-44-8)
- Alvimopan Impurity 7 (CAS CATO-C4X-11457)
- Alvimopan Impurity 8 (CAS 342639-35-4)
- Alvimopan Impurity 21 (CAS CATO-C4X-114521)
- Alvimopan Acyl Glucuronide (CAS 1260616-95-2)
Recommended Standards
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- Methyl 5-(3,4-dimethoxyphenyl)-2-(4-(dimethylamino)benzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 312938-63-9)
- 2-Imino-10-methyl-1-(2-morpholinoethyl)-3-tosyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606950-01-0)
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