Dexamethasone Impurity 103 CAS CATO-C4X-1165103
| CAS No. | CATO-C4X-1165103 |
| Molecular Formula | C54H89FO7 |
| Molecular Weight | 869.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dexamethasone Impurity 103 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Dexamethasone Impurity 103 (CAS CATO-C4X-1165103, C54H89FO7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, Dexamethasone Impurity 103 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 869.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C54H89FO7 |
| Molecular Weight | 869.28 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 100 (CAS CATO-C4X-1165100)
- Dexamethasone Impurity 102 (CAS CATO-C4X-1165102)
- Dexamethasone 21-Phosphate Dimer Sodium Salt (CAS CATO-C4X-116520)
- Dexamethasone Phosphate Diester (CAS CATO-C4X-116556)
- Dexamethasone-biotin (CAS 85679-56-7)
- Dexamethasone valerate (CAS CATO-C4X-1165125)
- Dexamethasone 21-Palmitate-d31 (CAS CATO-CCHM706040)
- Dexamethasone Octadecanoate (CAS CATO-C4X-116574)
Recommended Standards
- PBS 57 (CAS 898531-99-2)
- Coenzyme Q10-d6 (CAS 110971-02-3)
- Tilmicosin (CAS 108050-54-0)
- 5,6-Difluoro-2-(2-hexyldecyl)-4,7-bis(5-(trimethylstannyl)thiophen-2-yl)-2H-benzo[d][1,2,3]triazole (CAS 2365391-00-8)
- Eltrombopag Impurity 92 (CAS CATO-C4X-119892)
- Epinephrine /Adrenaline Impurity 138 (CAS CATO-C4X-1849138)
- Minocycline Impurity 65 (CAS CATO-C4X-169965)
- 4-(Cyclopropylmethoxy)-2-methylphenol (CAS 1243458-19-6)
- Benzyl 7-fluoro-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate (CAS 2306278-11-3)
- 3-(Bromomethyl)-6-chloro-2-fluoropyridine (CAS 1807004-45-0)
- (S)-5-amino-1'-((2-(trimethylsilyl)ethoxy)methyl)-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one (CAS 939016-96-3)
- N-(2-Bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide (CAS 878984-55-5)
- 3-Bromo-7-methoxy-2H-chromen-2-one (CAS 72167-80-7)
- Semaglutide238 (CAS CATO-C4X-2226238)
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