Rosuvastatin Impurity 166 CAS CATO-C4X-1169166

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1169166
Molecular FormulaC17H20FN3O2S
Molecular Weight349.42 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rosuvastatin Impurity 166 CAS CATO-C4X-1169166 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Rosuvastatin Impurity 166 (CAS CATO-C4X-1169166) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20FN3O2S and a molecular weight of 349.42 g/mol.

Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Rosuvastatin Impurity 166 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 349.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), Rosuvastatin Impurity 166 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H20FN3O2S
Molecular Weight349.42 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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