Lapatinib Impurity 33 (p-Toluenesulfonic acid) CAS CATO-C4X-119133
| CAS No. | CATO-C4X-119133 |
| Molecular Formula | C29H26ClFN4O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lapatinib Impurity 33 (p-Toluenesulfonic acid) (CAS CATO-C4X-119133), a pharmacopoeial impurity reference standard (molecular formula C29H26ClFN4O4SC7H8O3S, MW 753.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C29H26ClFN4O4SC7H8O3S, Lapatinib Impurity 33 (p-Toluenesulfonic acid) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 753.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lapatinib Impurity 33 (p-Toluenesulfonic acid) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H26ClFN4O4S C7H8O3S |
| Molecular Weight | 753.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Lapatinib Standards
- Lapatinib-d7 Ditosylate (CAS 1009307-24-7)
- Lapatinib Impurity 20 (CAS 1026818-86-9)
- Lapatinib Impurity 27 (CAS 104458-24-4)
- Lapatinib-d4 (CAS 1184264-15-0)
- Lapatinib Impurity 35 (CAS 1227853-06-6)
- Lapatinib Impurity 37 (CAS 1268997-70-1)
- Lapatinib Impurity 18 (CAS 1268997-70-1 (free base))
- Lapatinib Impurity 22 (CAS 1360431-86-2)
Recommended Standards
- Cefdinir Impurity 91 (CAS 206855-74-5)
- Arbidol Impurity 49 (CAS 20862-91-3)
- Luliconazole Impurity 10 (CAS 229334-55-8)
- (5-(3-Methoxyphenyl)pyridin-3-yl)methanamine (CAS 1356110-88-7)
- 1-[5-(Trimethylsilyl)-1,2-oxazol-3-yl]ethan-1-one (CAS 1631147-77-7)
- 3-Chloro-3-(4-methylpiperazinomethyl) benzophenone (CAS 898788-62-0)
- 3-Cyclopropoxy-4-fluoropyridin-2-amine (CAS 1243399-07-6)
- 6-(2,4-Dichlorophenyl)-3-(pyrrolidin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706428-48-9)
- Mal-NH-PEG8-CH2CH2COOPFP ester (CAS 2055023-14-6)
- D-β-Asp15-Tirzepatide (CAS CATO-CPTD788930)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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