Ceftazidime impurity 124 CAS CATO-C4X-1212124
| CAS No. | CATO-C4X-1212124 |
| Molecular Formula | C38H42ClN7O11S2 |
| Molecular Weight | 872.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ceftazidime impurity 124 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Ceftazidime impurity 124 (CAS CATO-C4X-1212124, C38H42ClN7O11S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ceftazidime impurity 124 (C38H42ClN7O11S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C38H42ClN7O11S2 |
| Molecular Weight | 872.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 2 |
Related Ceftazidime Standards
- Ceftazidime Impurity D (CAS CATO-C4X-12124)
- Ceftazidime Impurity 98 (CAS CATO-C4X-121298)
- Ceftazidime Impurity 14 (CAS CATO-C4X-121214)
- Ceftazidime Impurity 55 (CAS CATO-C4X-121255)
- Ceftazidime Impurity 99 (CAS CATO-C4X-121299)
- Ceftazidime Impurity 101 (CAS CATO-C4X-1212101)
- Ceftazidime Impurity 75 (CAS CATO-C4X-121275)
- Ceftazidime Impurity 31 (CAS CATO-C4X-121231)
Recommended Standards
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- Spiramycin EP Impurity B (CAS CATO-C4X-23252)
- （11E,13E）Tilmicosin-d3 (CAS 2714486-61-8)
- (SP-4-1)-[1,3-Bis[2,6-bis(1-ethylpropyl)phenyl]-4,5-dichloro-1,3-dihydro-2H-imidazol-2-ylidene]dichloro(3-chloropyridine-κN)palladium (CAS 1435347-24-2)
- Butylphthalide Impurity 34 (CAS CATO-C4X-181334)
- Lodoxamide Impurity 6 (CAS 75235-35-7)
- Tetrabenazine Impurity 33 (CAS CATO-C4X-274833)
- 6,8-Dimethoxyisoquinoline (CAS 13388-78-8)
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- (1-((Benzyloxy)methyl)-2,2-difluorocyclopropyl)methanol (CAS 2242957-73-7)
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