Ceftazidime Impurity 22 CAS CATO-C4X-121222

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-121222
Molecular FormulaC44H42N12O13S4
Molecular Weight1075.14 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ceftazidime Impurity 22 CAS CATO-C4X-121222 chemical structure

Description

CATO supplies Ceftazidime Impurity 22 (CAS CATO-C4X-121222), a pharmacopoeial impurity reference standard (molecular formula C44H42N12O13S4, MW 1075.14 g/mol) used for the identification and quantification of trace impurities in APIs.

Ceftazidime Impurity 22 (C44H42N12O13S4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC44H42N12O13S4
Molecular Weight1075.14 g/mol
Purity>90%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)30.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms12
Sulfur Atoms4

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