Ceftazidime Impurity 49 CAS CATO-C4X-121249
| CAS No. | CATO-C4X-121249 |
| Molecular Formula | C26H36N6O9S2 |
| Molecular Weight | 640.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ceftazidime Impurity 49 (CAS CATO-C4X-121249, C26H36N6O9S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ceftazidime Impurity 49 (C26H36N6O9S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 640.73 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H36N6O9S2 |
| Molecular Weight | 640.73 g/mol |
| Purity | ≥90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Ceftazidime Standards
- Ceftazidime impurity 120 (CAS CATO-C4X-1212120)
- Ceftazidime Impurity 100 (CAS CATO-C4X-1212100)
- Ceftazidime Impurity 86 (CAS CATO-C4X-121286)
- Ceftazidime Impurity 102 (CAS CATO-C4X-1212102)
- Ceftazidime Impurity 103 (CAS CATO-C4X-1212103)
- Ceftazidime EP Impurity E (CAS 102772-66-7)
- Ceftazidime Impurity 87 (CAS CATO-C4X-121287)
- Ceftazidime Impurity 92 (CAS CATO-C4X-121292)
Recommended Standards
- 4,4'-(3,8-Bis((4-aminophenyl)ethynyl)pyrene-1,6-diyl)dibenzaldehyde (CAS 2375652-85-8)
- N-nitroso Lercanidipine (CAS CATO-C4X-136471)
- Naloxone impurity 14 (CAS CATO-C4X-149314)
- Bumetanide impurity 106 (CAS CATO-C4X-1986106)
- Ilaprazole Impurity 74 (CAS 1807231-85-1)
- Salmeterol Impurity 26 (CAS CATO-C4X-105026)
- Telmisartan EP Impurity C (CAS 144702-26-1)
- 2-((4-Chlorophenyl)thio)propanehydrazide (CAS 1024477-91-5)
- Spiperone (CAS 749-02-0)
- 2-Amino-5-bromo-3-methylbenzohydrazide (CAS 1049139-87-8)
- 2-(Tert-butyl) 4-ethyl 3-hydroxy-2-azabicyclo[2.2.2]Octane-2,4-dicarboxylate (CAS 2306274-86-0)
- 15-Oxopentadecanoic acid (CAS 4587-29-5)
- 5-Ethynyl-2-fluoro-4-methylpyridine (CAS 1824459-89-3)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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