Roxatidine Impurity 51 CAS CATO-C4X-121351
| CAS No. | CATO-C4X-121351 |
| Molecular Formula | C21H30N2O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Roxatidine Impurity 51 (C21H30N2O6HCl) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Roxatidine Impurity 51 (CAS CATO-C4X-121351, C21H30N2O6HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Roxatidine Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H30N2O6 HCl |
| Molecular Weight | 442.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Roxatidine Standards
- Roxatidine Impurity 43 (CAS 100-83-4)
- Roxatidine Impurity 55 (CAS 100841-00-7)
- Roxatidine Impurity 21 (CAS 108441-34-5)
- Roxatidine Hemioxalate (CAS 110925-92-3)
- Roxatidine Impurity 58 (CAS 115062-97-0)
- Roxatidine Impurity 56 (CAS 132513-51-0)
- Roxatidine Impurity 34 (CAS 15504-60-6)
- Roxatidine Impurity 3 (CAS 195621-06-8)
Recommended Standards
- Suzetrigine Impurity 52 (CAS CATO-C4X-336952)
- Alprazolam impurity 27 (CAS CATO-C4X-146027)
- Canagliflozin Impurity 56 (CAS CATO-C4X-112356)
- 3-(4-Fluoro-3-(trifluoromethoxy)phenyl)propanoic acid (CAS 1240256-80-7)
- N-(3-Fluoro-4-((3-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)-2-(4-fluorophenyl)-1,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxamide (CAS 1221713-92-3)
- 6-(Bromomethyl)-2-pyridinecarboxaldehyde (CAS 1456534-07-8)
- Sodium 3,5-dioxotetrahydro-2H-pyran-4-ide (CAS 879127-67-0)
- 8-amino-3,7-dihydro-1H-purine-2,6-dione (CAS 5461-03-0)
- Methyl 2-(5-hydroxypyridin-2-yl)acetate (CAS 1256818-36-6)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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