Roxatidine Impurity 60 CAS CATO-C4X-121360
| CAS No. | CATO-C4X-121360 |
| Molecular Formula | C19H28N2O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Roxatidine Impurity 60 (C19H28N2O4HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Roxatidine Impurity 60 (CAS CATO-C4X-121360), a pharmacopoeial impurity reference standard (molecular formula C19H28N2O4HCl, MW 384.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Roxatidine Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H28N2O4 HCl |
| Molecular Weight | 384.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Roxatidine Standards
- Roxatidine Impurity 43 (CAS 100-83-4)
- Roxatidine Impurity 55 (CAS 100841-00-7)
- Roxatidine Impurity 21 (CAS 108441-34-5)
- Roxatidine Hemioxalate (CAS 110925-92-3)
- Roxatidine Impurity 58 (CAS 115062-97-0)
- Roxatidine Impurity 56 (CAS 132513-51-0)
- Roxatidine Impurity 34 (CAS 15504-60-6)
- Roxatidine Impurity 3 (CAS 195621-06-8)
Recommended Standards
- Dapagliflozin Impurity 69 (CAS 3093141-55-7)
- Brinzolamide Impurity 2 (CAS CATO-C4X-19402)
- Lemborexant Impurity 31 (CAS CATO-C4X-304231)
- N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanesulfonamide (CAS 1260151-60-7)
- 1-(3-Aminopropyl)-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine (CAS 823809-16-1)
- 1-[alpha-(4,6-Dimethoxypyrimidin-2-yl)benzyl]-piperazine (CAS 354563-89-6)
- 5-((M-tolyloxy)methyl)furan-2-carbaldehyde (CAS 1399662-02-2)
- Cyclooctanol (CAS 696-71-9)
- 1-(3-Nitrophenyl)-2-thiourea (CAS 709-72-8)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com