Cefamandole Impurity 35 CAS CATO-C4X-122135
| CAS No. | CATO-C4X-122135 |
| Molecular Formula | C12H14N6O4S2 |
| Molecular Weight | 370.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cefamandole Impurity 35.
CATO supplies Cefamandole Impurity 35 (CAS CATO-C4X-122135), a pharmacopoeial impurity reference standard (molecular formula C12H14N6O4S2, MW 370.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Cefamandole Impurity 35 (C12H14N6O4S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N6O4S2 |
| Molecular Weight | 370.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Cefamandole Standards
- Cefamandole Impurity 22 (CAS CATO-C4X-122122)
- Cefamandole Nafate EP Impurity A (CAS CATO-C4X-122131)
- Cefamandole Impurity 21 (CAS CATO-C4X-122121)
- Cefamandole Impurity 14 (CAS CATO-C4X-122114)
- Cefamandole Impurity 33 (CAS CATO-C4X-122133)
- Cefamandole Impurity 24 (CAS 51818-85-0)
- Cefamandole Impurity 20 (CAS 49753-68-6)
- Cefamandole Impurity 10 (CAS CATO-C4X-122110)
Recommended Standards
- Lenalidomide-C5-azide (CAS 2399455-78-6)
- Fezolinetant Impurity 26 (CAS CATO-C4X-327026)
- 8-(2-(1-(4-Hydroxyphenyl)ethylidene)hydrazinyl)-7-isobutyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione (CAS 682776-57-4)
- 2,6-Bis(4-azidobenzal)-4-methylcyclohexanone (CAS 5284-79-7)
- Rasagiline Impurity 43 (CAS CATO-C4X-191343)
- Cefotaxime Impurity 35 (CAS CATO-C4X-120135)
- Baricitinib Impurity 7 (CAS CATO-C4X-22607)
- N,5-Dimethyl-4,5-dihydro-1H-pyrazole-1-carboxamide (CAS 71233-33-5)
- 1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-(methoxymethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 312496-15-4)
- (R)-Acenocoumarol (CAS 66556-77-2)
- 5-Iodo-4-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 1936218-08-4)
- tert-Butyl 4-methoxy-1-oxa-7-azaspiro[4.4]non-3-ene-7-carboxylate (CAS 2177264-54-7)
- 5-(1h-1,2,4-Triazol-1-yl)pentanoic acid (CAS 1038972-79-0)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com