Netupitant Impurity 35 CAS CATO-C4X-122335
| CAS No. | CATO-C4X-122335 |
| Molecular Formula | C13H12F6O2 |
| Molecular Weight | 314.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Netupitant Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Netupitant Impurity 35 (CAS CATO-C4X-122335, C13H12F6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Netupitant Impurity 35 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 314.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H12F6O2 |
| Molecular Weight | 314.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Netupitant Standards
- Netupitant Impurity 30 (CAS CATO-C4X-122330)
- Netupitant Impurity 37 (CAS CATO-C4X-122337)
- Netupitant Impurity 3 (CAS CATO-C4X-12233)
- Netupitant Impurity 5 (CAS CATO-C4X-12235)
- Netupitant Impurity 31 (CAS 1444338-30-0)
- Netupitant Impurity 26 (CAS CATO-C4X-122326)
- Netupitant Impurity 41 (CAS CATO-C4X-122341)
- Netupitant Impurity 42 (CAS CATO-C4X-122342)
Recommended Standards
- Tert-butyl 2,4-bis(trifluoromethyl)benzoate (CAS 2586126-78-3)
- Bilastine impurity 132 (CAS 361382-25-4)
- tert-Butyl 2-(2-bromoethyl)benzylcarbamate (CAS 496917-86-3)
- 1,2-Bis(4-(trifluoromethyl)phenyl)ethyne (CAS 119757-51-6)
- Paliperidone USP Related Compound A (CAS 849903-79-3)
- Atrasentan Impurity 115 (CAS 1073836-98-2)
- Elagolix Impurity 99 (CAS CATO-C4X-206899)
- 1-(4-Fluoro-2-(trifluoromethyl)phenyl)-N,N-dimethylpiperidin-4-amine (CAS 1707605-08-0)
- (S)-2-(tert-butoxycarbonyl)-9-formyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid (CAS 327603-46-3)
- 3-Methoxy-N-methylcyclobutan-1-amine (CAS 1520446-07-4)
- 2,6-Dichloro-5-methoxypyrimidin-4-amine (CAS 1126320-54-4)
- 4-Phenyl-3-(piperidin-1-ylmethyl)dihydrofuran-2(3H)-one (CAS 99518-92-0)
- 4-((1S,4r)-4-propylcyclohexyl)phenyl 4'-pentyl-[1,1'-bi(cyclohexane)]-4-carboxylate (CAS 91545-93-6)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com