Emtricitabine Impurity 60 CAS CATO-C4X-123260
| CAS No. | CATO-C4X-123260 |
| Molecular Formula | C8H9FN2O5S |
| Molecular Weight | 264.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Emtricitabine Impurity 60.
CATO supplies Emtricitabine Impurity 60 (CAS CATO-C4X-123260), a pharmacopoeial impurity reference standard (molecular formula C8H9FN2O5S, MW 264.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Emtricitabine Impurity 60 (C8H9FN2O5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Emtricitabine Impurity 60 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9FN2O5S |
| Molecular Weight | 264.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Emtricitabine Standards
- Emtricitabine Impurity 24 (CAS 1160303-44-5)
- Emtricitabine S-oxide(Mixture) (CAS 152128-77-3)
- Emtricitabine Enantiomer S-oxide(S-Isomer) (CAS CATO-C4X-123232)
- Emtricitabine Enantiomer S-oxide(R-Isomer) (CAS CATO-C4X-123233)
- Emtricitabine impurity 42 (CAS 2101981-64-8)
- Emtricitabine impurity 43 (CAS CATO-C4X-123243)
- Emtricitabine Ring-opening Impurity (CAS CATO-C4X-123212)
- Emtricitabine impurity 50 (CAS CATO-C4X-123250)
Recommended Standards
- (4S)-3-Cbz-2-oxo-Imidazolidine-4-carboxylic acid (CAS 59760-01-9)
- Tucidinostat Impurity 1 (CAS CATO-C4X-31501)
- Zilascorb (CAS 20664-60-2)
- Flumequine-13C3 (CAS 1185049-09-5)
- Mianserin Impurity 91 (CAS 1192015-20-5)
- Dapagliflozin Impurity 47 (CAS CATO-C4X-113847)
- Brivaracetam Impurity 77 (CAS CATO-C4X-200777)
- 2-Aminobenzimidazole-5-carbonitrile (CAS 63655-40-3)
- 1,4-Dichloro-2,5-bis(dichloromethyl)benzene (CAS 41999-84-2)
- N-Cyclopropyl-4-methyl-N-((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)benzamide (CAS 606095-17-4)
- (E)-2-(1,3-Benzodioxol-5-yl)-3-[4-(3-formyl-1H-indol-1-yl)phenyl]-2-propenenitrile (CAS 860650-54-0)
- 4,4-Diethyl-2,6-dioxopiperidine-3,5-dicarbonitrile (CAS 80721-13-7)
- 4-Cyclopropyl-4-oxobutanoic acid (CAS 53712-75-7)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com