Bisoprolol EP Impurity F Hemifumarate CAS CATO-C4X-124743
| CAS No. | CATO-C4X-124743 |
| Molecular Formula | 2*C18H31NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Bisoprolol EP Impurity F Hemifumarate (CAS CATO-C4X-124743, C18H31NO4C4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Bisoprolol EP Impurity F Hemifumarate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 441.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Bisoprolol EP Impurity F Hemifumarate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C18H31NO4 C4H4O4 |
| Molecular Weight | 441.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Bisoprolol Standards
- Bisoprolol Impurity 79 (CAS 1039828-27-7)
- Bisoprolol Fumarate (CAS 104344-23-2)
- Bisoprolol-D6 Fumarate (CAS 104344-23-2(Unlabelled))
- Bisoprolol Impurity 49 (CAS 104857-48-9)
- Bisoprolol Fumarate (CAS 105878-43-1)
- Bisoprolol Impurity 62 Formate (CAS 109791-18-6(free base))
- Bisoprolol Impurity N5 (CAS 109791-19-7)
- Bisoprolol EP Impurity T (CAS 1173203-26-3)
Recommended Standards
- Nilotinib Impurity 16 (CAS 641571-13-3)
- Avanafil Impurity 137 (CAS CATO-C4X-1118137)
- Mianserin Impurity 49 (CAS CATO-C4X-136949)
- benzyl({2-[benzyl(methyl)amino]ethyl})amine (CAS 84425-29-6)
- 2,6-Dibromo-4-methylbenzonitrile (CAS 59596-31-5)
- Clevidipine impurity 37 (CAS CATO-C4X-101537)
- (2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanol (CAS 443955-89-3)
- 3-Amino-N,4-bis(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 333777-93-8)
- Lifitegrast Impurity 33 (CAS CATO-C4X-240933)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com