Bisoprolol EP Impurity G HCl CAS CATO-C4X-124750
| CAS No. | CATO-C4X-124750 |
| Molecular Formula | C19H33NO5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Bisoprolol EP Impurity G HCl (CAS CATO-C4X-124750, C19H33NO5HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Bisoprolol EP Impurity G HCl is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 391.93 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H33NO5 HCl |
| Molecular Weight | 391.93 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bisoprolol Standards
- Bisoprolol Impurity 79 (CAS 1039828-27-7)
- Bisoprolol Fumarate (CAS 104344-23-2)
- Bisoprolol-D6 Fumarate (CAS 104344-23-2(Unlabelled))
- Bisoprolol Impurity 49 (CAS 104857-48-9)
- Bisoprolol Fumarate (CAS 105878-43-1)
- Bisoprolol Impurity 62 Formate (CAS 109791-18-6(free base))
- Bisoprolol Impurity N5 (CAS 109791-19-7)
- Bisoprolol EP Impurity T (CAS 1173203-26-3)
Recommended Standards
- Pantoprazole EP Impurity C (CAS 97963-62-7)
- Hydantoin Impurity 27 (CAS 121565-48-8)
- Epinastine Impurity 13 HCl (CAS 141342-69-0)
- Gliclazide Impurity 12 (CAS 936091-14-4)
- trans-Stilbene-d12 (CAS 16341-52-9)
- 6-(Furan-3-yl)-1H-indazole (CAS 885271-98-7)
- Indacaterol Impurity 29 (CAS 1446354-19-3)
- Itaconic Acid (CAS 97-65-4)
- (3AR,6aS)-2-(isobutylsulfonyl)octahydropyrrolo[3,4-c]pyrrole (CAS 1690025-29-6)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
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