Perindopril Impurity 80 HCl CAS CATO-C4X-125280
| CAS No. | CATO-C4X-125280 |
| Molecular Formula | C19H32N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 404.93 g/mol gives Perindopril Impurity 80 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Perindopril Impurity 80 HCl (CAS CATO-C4X-125280) is a certified pharmaceutical impurity reference standard with the molecular formula C19H32N2O5HCl and a molecular weight of 404.93 g/mol.
Based on its molecular formula C19H32N2O5HCl, Perindopril Impurity 80 HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 404.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H32N2O5 HCl |
| Molecular Weight | 404.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Perindopril Standards
- Perindopril Impurity N3 (CAS 1004292-98-1)
- Perindopril T-Butylamine (CAS 107133-36-8)
- Perindopril Impurity N1 (CAS 108507-42-2)
- Perindopril Impurity 1 HCl (CAS 111013-52-6)
- Perindopril EP Impurity L (CAS 111836-22-7)
- Perindopril Acyl-beta-D-Glucuronide (CAS 120398-66-5)
- Perindopril Benzyl Ester (CAS 122454-52-8)
- Perindopril EP Impurity F (CAS 129970-98-5)
Recommended Standards
- N-Nitroso Etilefrine EP Impurity F (CAS 20689-96-7)
- Ursodeoxycholic Acid Impurity 114 (CAS 51446-79-8)
- Ozenoxacin Impurity 66 (CAS CATO-C4X-113966)
- 2,8-Difluorodibenzo[b,d]thiophene (CAS 80017-76-1)
- 6-Fluoroquinoline-2-thiol (CAS 1330753-13-3)
- 2-[(5-cyclohexyl-4-methyl-4h-1,2,4-triazol-3-yl)sulfanyl]acetic acid (CAS 462066-86-0)
- Methyl 4-Bromo-1H-indazole-6-carboxylate (CAS 885518-47-8)
- n-(2,3-Dimethylbenzyl)-3-methoxypropan-1-amine (CAS 1249935-34-9)
- 3-((4-Chlorobenzyl)oxy)-5-methoxythiophene-2-carboxylic acid (CAS 1708401-59-5)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com