Perindopril Impurity 84 CAS CATO-C4X-125284
| CAS No. | CATO-C4X-125284 |
| Molecular Formula | C19H32N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Perindopril Impurity 84 (C19H32N2O5HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Perindopril Impurity 84 (CAS CATO-C4X-125284) is a certified pharmaceutical impurity reference standard with the molecular formula C19H32N2O5HCl and a molecular weight of 404.93 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H32N2O5 HCl |
| Molecular Weight | 404.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Perindopril Standards
- Perindopril Impurity N3 (CAS 1004292-98-1)
- Perindopril T-Butylamine (CAS 107133-36-8)
- Perindopril Impurity N1 (CAS 108507-42-2)
- Perindopril Impurity 1 HCl (CAS 111013-52-6)
- Perindopril EP Impurity L (CAS 111836-22-7)
- Perindopril Acyl-beta-D-Glucuronide (CAS 120398-66-5)
- Perindopril Benzyl Ester (CAS 122454-52-8)
- Perindopril EP Impurity F (CAS 129970-98-5)
Recommended Standards
- Olodaterol Impurity 10 (CAS CATO-C4X-19440)
- Macitentan Impurity 22 (CAS CATO-C4X-117522)
- Octreotide impurity 4 (CAS CATO-C4X-15204)
- Ethyl 2-(3-aminoazetidin-1-yl)acetate (CAS 1482895-11-3)
- 2-(2-Chloro-4-formylphenoxy)-N-(3-chloro-4-methylphenyl)acetamide (CAS 694468-76-3)
- 3-(4-(Difluoromethoxy)phenyl)propanoic acid (CAS 1000932-18-2)
- Methyl 3-fluoro-8-methoxycinnoline-6-carboxylate (CAS 2721376-52-7)
- 7-(Thiazol-4-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine (CAS 2137543-10-1)
- N-[(3-Chloro-2-fluorophenyl)methyl]cyclopropanamine (CAS 878001-21-9)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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