Bendamustine Impurity 6 CAS CATO-C4X-12716
| CAS No. | CATO-C4X-12716 |
| Molecular Formula | C18H25Cl2N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bendamustine Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Bendamustine Impurity 6 (CAS CATO-C4X-12716), a pharmacopoeial impurity reference standard (molecular formula C18H25Cl2N3O2HCl, MW 422.77 g/mol) used for the identification and quantification of trace impurities in APIs.
Bendamustine Impurity 6 (C18H25Cl2N3O2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H25Cl2N3O2 HCl |
| Molecular Weight | 422.77 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Bendamustine Standards
- Bendamustine impurity 33 (CAS 109882-25-9)
- Bendamustine Impurity 2 (CAS 109882-26-0)
- Bendamustine USP Related Compound E (CAS 109882-27-1)
- Bendamustine Dihydroxy Impurity (CAS 109882-29-3)
- Bendamustine USP Related Compound A (CAS 109882-30-6)
- Bendamustine-D8 Hydrochloride (CAS 1134803-33-0)
- Bendamustine Impurity 7 (CAS 1138238-08-0)
- Bendamustine Dideschloroethyl Acid Hydrochloride (CAS 1179363-38-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com