Nafamostat impurity 105 HCl CAS CATO-C4X-1332105
| CAS No. | CATO-C4X-1332105 |
| Molecular Formula | C27H23N7O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Nafamostat impurity 105 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Nafamostat impurity 105 HCl (CAS CATO-C4X-1332105, C27H23N7O4HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C27H23N7O4HCl, Nafamostat impurity 105 HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 545.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C27H23N7O4 HCl |
| Molecular Weight | 545.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Nafamostat Standards
- Nafamostat Impurity 61 (CAS 1026613-65-9)
- Nafamostat impurity 110 (CAS 107490-62-0)
- Nafamostat Impurity 65 (CAS 107490-62-0（free base）)
- Nafamostat Impurity N3 (CAS 115325-88-7)
- Nafamostat Impurity 26 (CAS 1192026-58-6)
- Nafamostat Impurity 63 (CAS 121714-82-7)
- Nafamostat Impurity 37 (CAS 122228-09-5)
- Nafamostat Impurity 35 (CAS 130200-58-7)
Recommended Standards
- Dapagliflozin Impurity 157 (CAS CATO-C4X-1138157)
- Pinaverium Bromide Impurity 44 (CAS 87325-77-7)
- Cenobamate Impurity 18 (CAS CATO-C4X-241618)
- 2-(Difluoromethyl)-6-methoxy-3-(trifluoromethoxy)pyridine-4-acetic acid (CAS 1806750-37-7)
- Ammonium pentafluoropropionate (CAS 2730-58-7)
- 1-(3-Chloropyridin-2-yl)-n-methylmethanamine hydrochloride (CAS 2680615-30-7)
- 2-(3-Bromophenyl)-1,3-dioxolane (CAS 17789-14-9)
- 2-(Tert-butoxycarbonyl)octahydro-1H-cyclopenta[c]pyridine-6-carboxylic acid (CAS 1559845-82-7)
- 9,3’:6’,9’’-Tercarbazole (CAS 606129-90-2)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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