Sunitinib Impurity 83 CAS CATO-C4X-133383
| CAS No. | CATO-C4X-133383 |
| Molecular Formula | C16H8F2N2O2 |
| Molecular Weight | 298.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Sunitinib Impurity 83 (CAS CATO-C4X-133383) is a certified pharmaceutical impurity reference standard with the molecular formula C16H8F2N2O2 and a molecular weight of 298.24 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Sunitinib Impurity 83 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 298.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Sunitinib Impurity 83 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H8F2N2O2 |
| Molecular Weight | 298.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Sunitinib Standards
- Sunitinib Impurity 33 (CAS 1186651-51-3)
- Sunitinib Impurity 22 (CAS 452105-33-8)
- Sunitinib Impurity 68 (CAS CATO-C4X-133368)
- Sunitinib Impurity 71 (CAS 83615-76-3)
- Sunitinib Impurity 35 (CAS CATO-C4X-133335)
- Sunitinib Impurity 84 (CAS CATO-C4X-133384)
- Sunitinib Impurity 89 (CAS CATO-C4X-133389)
- Sunitinib Impurity 88 (CAS CATO-C4X-133388)
Recommended Standards
- Sitagliptin Impurity 71 (CAS CATO-C4X-114471)
- 4-Amino-7-phenyl-7H-pyrrolo[2,3-d]pyrimidine-5,6-dicarboxylic acid (CAS 101153-20-2)
- Sitagliptin Impurity 70 (CAS CATO-C4X-114470)
- 6-Methyl-2-(5-nitrofuran-2-yl)quinoline-4-carboxylic acid (CAS 116761-66-1)
- Gadodiamide Impurity 10 (CAS CATO-C4X-314310)
- Fudosteine impurity 74 (CAS CATO-C4X-144774)
- Crizotinib impurity 38 (CAS CATO-C4X-102538)
- Ethyl 3-(1-naphthoyl)-5-(pyridin-2-yl)indolizine-1-carboxylate (CAS 618070-13-6)
- CAS 287389-39-3 (CAS 287389-39-3)
- Potassium [2,2'-biquinoline]-4,4'-dicarboxylate (CAS 63451-34-3)
- 2-((4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-ethylphenyl)acetamide (CAS 557069-45-1)
- 5-(Ethylsulfonyl)-4-(3-fluorophenyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1710833-71-8)
- 1-[(4-methoxyphenyl)methyl]azetidine-2-carboxylic acid (CAS 1042413-93-3)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
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