Levofolinate Impurity 16 CAS CATO-C4X-133516
| CAS No. | CATO-C4X-133516 |
| Molecular Formula | C20H22N8O8 |
| Molecular Weight | 502.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Levofolinate Impurity 16 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Levofolinate Impurity 16 (CAS CATO-C4X-133516) is a certified pharmaceutical impurity reference standard with the molecular formula C20H22N8O8 and a molecular weight of 502.44 g/mol.
Based on its molecular formula C20H22N8O8, Levofolinate Impurity 16 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 502.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Levofolinate Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H22N8O8 |
| Molecular Weight | 502.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Levofolinate Standards
- Levofolinate Impurity 17 (CAS CATO-C4X-133517)
- Levofolinate Impurity 20 (CAS CATO-C4X-133520)
- Levofolinate Impurity 21 (CAS CATO-C4X-133521)
- Calcium Levofolinate EP Impurity B (CAS CATO-C4X-13353)
- Levofolinate Impurity 18 (CAS CATO-C4X-133518)
- Calcium Levofolinate EP Impurity I (CAS 31690-11-6)
- Levofolinate Impurity 8 (CAS 4299-32-5)
- Calcium Levofolinate Pentahydrate - Impurity G (Dihydrate Salt) (CAS 207226-40-2)
Recommended Standards
- tert-Butyl (20-bromo-3,6,9,12,15,18-hexaoxaicosyl)(methyl)carbamate (CAS 2874309-78-9)
- 2,6-Bis(Trifluoromethyl)-4-Pyrimidinamine (CAS 717-61-3)
- 3-(Bis(3,5-difluorophenyl)phosphino)-[1,1':3',1''-terphenyl]-2'-ol (CAS 185543-94-6)
- Vilanterol Impurity 22 (CAS CATO-C4X-193522)
- Valsartan Impurity 150 (CAS CATO-C4X-1057150)
- Furosemide Impurity 52 (CAS CATO-C4X-140252)
- Sitafloxacin Impurity 30 (CAS CATO-C4X-115530)
- Ethyl 2-bromo-4-methoxybenzoate (CAS 1208075-63-1)
- 4,6-Dichloro-2-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1805333-67-8)
- 2-Benzoyl-3-{[3-(trifluoromethyl)benzenesulfonyl]methyl}-1-benzofuran (CAS 338423-88-4)
- N-(5-tert-butylisoxazol-3-yl)propanamide (CAS 74011-62-4)
- 10-Isopentyl-2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-one (CAS 58059-23-7)
- 5-Cyclopropoxy-2-ethyl-N-methylaniline (CAS 1243318-95-7)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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