Duloxetine Impurity 35 CAS CATO-C4X-133635
| CAS No. | CATO-C4X-133635 |
| Molecular Formula | C18H18N2O2S |
| Molecular Weight | 326.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Duloxetine Impurity 35 (CAS CATO-C4X-133635, C18H18N2O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Duloxetine Impurity 35 (C18H18N2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Duloxetine Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18N2O2S |
| Molecular Weight | 326.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Duloxetine Standards
- Duloxetine Impurity (CAS 2680527-91-5)
- Duloxetine Impurity 32 (CAS 2680527-91-5 (racemic))
- Duloxetine Impurity 33 (CAS CATO-C4X-133633)
- Duloxetine Impurity 34 (CAS CATO-C4X-133634)
- Duloxetine Impurity 43 (CAS CATO-C4X-133643)
- Duloxetine 4-Hydroxy N-Methyl (CAS 1346601-61-3)
- Duloxetine Impurity 13 (CAS 116817-12-0)
- Duloxetine Impurity 6 (CAS 132335-46-7)
Recommended Standards
- Cefcapene Impurity 34 (CAS 158743-37-4)
- Cefcapene Impurity 35 (CAS 158743-45-4)
- N-(3-Methyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5-yl)butyramide (CAS 1020488-02-1)
- (4-((1H-Benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)(thiophen-2-yl)methanone (CAS 1172356-10-3)
- Valsartan Impurity 47 (CAS 783369-52-8)
- Clopidogrel EP impurity D Sulfate (CAS 1421283-60-4 (free base))
- Eldecalcitol Impurity 43 (CAS CATO-C4X-214043)
- 4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-N-[(1Z)-{[(4-chlorophenyl)methoxy]imino}methyl]benzamide (CAS 338979-33-2)
- 5-(4-Chlorophenyl)-3-{[(4-methylphenyl)sulfanyl]methyl}-1,2-oxazole (CAS 551921-52-9)
- Clevidipine butyrate Impurity 4 (CAS 188649-48-1)
- 4-Ethyl-6-isopropyl-2-oxo-2H-chromene-3-carbonitrile (CAS 1352522-18-9)
- 2,7-Diaminoanthraquinone (CAS 605-44-7)
- 3-Nitro-4-(phenylamino)benzoic acid (CAS 16927-49-4)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com