Clindamycin Impurity 145 CAS CATO-C4X-1341145
| CAS No. | CATO-C4X-1341145 |
| Molecular Formula | C21H35ClN2O5S |
| Molecular Weight | 463.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Clindamycin Impurity 145 (CAS CATO-C4X-1341145, C21H35ClN2O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H35ClN2O5S, Clindamycin Impurity 145 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 463.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H35ClN2O5S |
| Molecular Weight | 463.03 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Clindamycin Standards
- Clindamycin Impurity 82 (CAS CATO-C4X-134182)
- Clindamycin Impurity 84 (CAS CATO-C4X-134184)
- Clindamycin Impurity 85 (CAS CATO-C4X-134185)
- Clindamycin Impurity 13 (CAS 147650-54-2)
- Clindamycin Impurity 144 (CAS CATO-C4X-1341144)
- Clindamycin Impurity 152 (CAS CATO-C4X-1341152)
- Clindamycin Impurity 34 (CAS CATO-C4X-134134)
- Clindamycin Impurity 20 (CAS CATO-C4X-1341120)
Recommended Standards
- 4-Chloro-N-(1-{4-methyl-5-[(2-methylprop-2-en-1-yl)sulfanyl]-4H-1,2,4-triazol-3-yl}-2-phenylethyl)benzene-1-sulfonamide (CAS 338794-34-6)
- (5-Chloro-2-phenoxyphenyl)triphenylsilane (CAS 18866-43-8)
- Lead(II) iodide (CAS 10101-63-0)
- N1-{4-[2-chloro-5-(trifluoromethyl)phenoxy]-2-fluorophenyl}-2,3,3-trichloroacrylamide (CAS 243963-14-6)
- Dotinurad Impurity 37 (CAS CATO-C4X-249437)
- Amoxicillin Impurity 60 (CAS CATO-C4X-114860)
- Ampicillin Impurity 54 (CAS CATO-C4X-144354)
- (2R)-3-amino-2-fluoropropanoic acid hydrochloride (CAS 1414874-23-9)
- 2-(1-Benzhydrylazetidin-3-yl)propane-1,3-diol (CAS 1375303-15-3)
- 5-Methyl-6-methylsulfanyl-pyridine-3-carbaldehyde (CAS 1289077-74-2)
- 2-Chlor-4'-methyl-biphenyl (CAS 19493-33-5)
- 4-(Pyridin-2-yloxy)cyclohexane-1-carboxylic acid (CAS 2050002-60-1)
- 1-(1-(4-Methoxyphenyl)-5-methyl-1H-pyrazol-4-yl)ethan-1-one (CAS 96723-55-6)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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