Lincomycin Impurity 11 CAS CATO-C4X-134211
| CAS No. | CATO-C4X-134211 |
| Molecular Formula | C18H34N2O6S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lincomycin Impurity 11 (C18H34N2O6SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Lincomycin Impurity 11 (CAS CATO-C4X-134211, C18H34N2O6SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H34N2O6S HCl |
| Molecular Weight | 443.00 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Lincomycin Standards
- Lincomycin B Hydrochloride (CAS 11021-35-5)
- Lincomycin EP Impurity E (CAS 13380-36-4)
- Lincomycin EP Impurity C (CAS 14600-41-0)
- Lincomycin EP Impurity F (CAS 14810-93-6)
- Lincomycin EP Impurity F Dihydrate (CAS 14810-93-6(Anhydrate CAS))
- Lincomycin EP Impurity D(Clindamycin EP Impurity D) (CAS 17017-22-0)
- Lincomycin sulfone Impurity (CAS 198080-68-1)
- Lincomycin Sulfoxide (Mixture of Diastereomers) (CAS 22083-92-7)
Recommended Standards
- Ensifentrine impurity 11 (CAS CATO-C4X-335311)
- Roxithromycin Impurity 14 (CAS CATO-C4X-130314)
- Desmopressin EP Impurity B (CAS CATO-C4X-221524)
- 2-Chloro-4-ethylbenzo[d]oxazole (CAS 1803863-78-6)
- 1-((1-Cyanocyclohexyl)amino)-1-oxopropan-2-yl 2-(cyclohexyl(methyl)carbamoyl)benzoate (CAS 876944-11-5)
- N-methoxy-N-methylisoquinoline-3-carboxamide (CAS 362057-20-3)
- 5-((6,7-Dimethoxybenzo[d][1,3]dioxol-5-yl)methyl)-4,5-dihydroisoxazole-3-carboxamide (CAS 924871-24-9)
- 2,4-Dibromo-6-(3,4,5-tribromo-1H-pyrrol-2-yl)phenol (CAS 10245-81-5)
- Gabapentin Impurity 23 (CAS CATO-C4X-165423)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
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