Avibactam Impurity 75 CAS CATO-C4X-134875
| CAS No. | CATO-C4X-134875 |
| Molecular Formula | C12H20N4O8S |
| Molecular Weight | 380.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Avibactam Impurity 75.
Avibactam Impurity 75 (CAS CATO-C4X-134875) is a certified pharmaceutical impurity reference standard with the molecular formula C12H20N4O8S and a molecular weight of 380.37 g/mol.
Avibactam Impurity 75 (C12H20N4O8S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20N4O8S |
| Molecular Weight | 380.37 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Avibactam Standards
- Avibactam Impurity 142 (CAS CATO-C4X-1348142)
- Avibactam Impurity 114 (CAS CATO-C4X-1348114)
- Avibactam Impurity 14 (CAS CATO-C4X-134814)
- Avibactam Impurity 140 (CAS CATO-C4X-1348140)
- Avibactam impurity 112 (CAS 1416134-58-1&1463522-16-8)
- Avibactam Impurity 132 (CAS CATO-C4X-1348132)
- Avibactam Impurity 20 (CAS CATO-C4X-134820)
- Avibactam Impurity 139 (CAS CATO-C4X-1348139)
Recommended Standards
- N'-[2-(4-Fluorophenoxy)ethanimidoyl]-2-phenoxypyridine-3-carbohydrazide (CAS 337928-94-6)
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- ethyl (2Z)-{3-[(6-nitro-4H-1,3-benzodioxin-8-yl)methyl]-4-oxo-1,3-thiazolidin-2-ylidene}acetate (CAS 848299-03-6)
- Upadacitinib Impurity 144 (CAS CATO-C4X-2405144)
- Anagrelide Impurity 16 (CAS CATO-C4X-224016)
- Mianserin EP Impurity D (CAS 157994-98-4)
- Pimobendan Impurity 9 (CAS CATO-C4X-24619)
- 1-Phenyl-4-(thiophen-3-yl)-1H-pyrazol-5-amine (CAS 165404-13-7)
- 2-(2-Mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-N-(4-methoxyphenyl)acetamide (CAS 1142206-71-0)
- 3-(1-((5-Chlorothiophen-2-yl)sulfonyl)pyrrolidin-3-yl)thiazolidine-2,4-dione (CAS 1795481-56-9)
- n-(4-Aminobutyl)-2-bromoacetamide (CAS 16504-93-1)
- 2-Amino-4-(1-hydroxyethyl)-1H-imidazol-5-ol (CAS 339345-77-6)
- N,N-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-sulfonamide (CAS 1256360-13-0)
- (Des-His1,Glu?)-Glucagon (1-29) amide (human, rat, porcine) (CAS 110084-95-2)
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