Bromocriptine EP Impurity D TFA Salt CAS CATO-C4X-136110

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-136110
Molecular FormulaC16H15BrN2O2
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bromocriptine EP Impurity D TFA Salt CAS CATO-C4X-136110 chemical structure

Description

The occurrence of Bromocriptine EP Impurity D TFA Salt is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Bromocriptine EP Impurity D TFA Salt (CAS CATO-C4X-136110), a pharmacopoeial impurity reference standard (molecular formula C16H15BrN2O2C2HF3O2, MW 461.23 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Bromocriptine EP Impurity D TFA Salt (C16H15BrN2O2C2HF3O2) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Bromocriptine EP Impurity D TFA Salt meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H15BrN2O2 C2HF3O2
Molecular Weight461.23 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF/Br-containing
Nitrogen Atoms2

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