Metoprolol Impurity 44 CAS CATO-C4X-136744
| CAS No. | CATO-C4X-136744 |
| Molecular Formula | C13H18N2O4 |
| Molecular Weight | 266.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metoprolol Impurity 44.
CATO supplies Metoprolol Impurity 44 (CAS CATO-C4X-136744), a pharmacopoeial impurity reference standard (molecular formula C13H18N2O4, MW 266.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Metoprolol Impurity 44 (C13H18N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Metoprolol Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18N2O4 |
| Molecular Weight | 266.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Metoprolol Standards
- Metoprolol impurity 45 (CAS CATO-C4X-136745)
- Metoprolol Impurity 2 (Mixture of Z and E Isomers) (CAS 82961-02-2)
- Metoprolol Impurity 23 (CAS 109632-11-3)
- Metoprolol EP Impurity E (CAS 163685-38-9)
- Metoprolol (CAS 51384-51-1)
- Metoprolol (CAS 37350-58-6)
- Metoprolol S-Isomer (CAS 81024-42-2)
- Metoprolol impurity 1 (CAS 150332-88-0)
Recommended Standards
- Carbamazepine Impurity 14 (CAS CATO-C4X-118114)
- Salbutamol impurity 91 (CAS CATO-C4X-1176191)
- Ampicillin Impurity 101 (CAS CATO-C4X-1443101)
- Oxcarbazepine EP Impurity B (CAS 28721-09-7)
- Budesonide Impurity 20 (CAS CATO-C4X-138920)
- Indacaterol Impurity 45 (CAS CATO-C4X-150045)
- Ceftiofur Impurity 7 (CAS CATO-C4X-15817)
- 2-(1-Chloroethyl)-5-(3,4-dimethylphenyl)-1,3,4-oxadiazole (CAS 1156945-18-4)
- 3-Formylimidazo[1,2-a]pyridine-7-carboxylic acid (CAS 1033202-06-0)
- 1-Propyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874291-01-7)
- 2-Ethylbenzofuran-6-amine (CAS 27408-35-1)
- N-(Bicyclo[2.2.1]hept-5-en-2-ylmethyl)methanesulfonamide (CAS 287923-89-1)
- (R)-4-(4-Fluorophenyl)pyrrolidin-2-one (CAS 894421-64-8)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com