Daptomycin Impurity 8 CAS CATO-C4X-13788
| CAS No. | CATO-C4X-13788 |
| Molecular Formula | C44H66N10O15 |
| Molecular Weight | 975.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Daptomycin Impurity 8 (C44H66N10O15) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Daptomycin Impurity 8 (CAS CATO-C4X-13788, C44H66N10O15) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Daptomycin Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H66N10O15 |
| Molecular Weight | 975.05 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 10 |
Related Daptomycin Standards
- Daptomycin Impurity 13 (CAS CATO-C4X-137813)
- Daptomycin Impurity 34 (CAS CATO-C4X-137834)
- Daptomycin Impurity 16 (CAS CATO-C4X-137816)
- Daptomycin Impurity 18 (CAS CATO-C4X-137818)
- Daptomycin Impurity 6 (CAS CATO-C4X-13786)
- Daptomycin Impurity 11 (CAS CATO-C4X-137811)
- Daptomycin Impurity 20 (CAS CATO-C4X-137820)
- Daptomycin Impurity 38 (CAS CATO-C4X-137838)
Recommended Standards
- 5,10,15,20-Tetra(3,4,5-trimethoxyphenyl)porphyrin (CAS 74684-35-8)
- Sar-[D-Phe8]-des-Arg9-Bradykinin (CAS 126959-88-4)
- Hypertrehalosemic Hormone (Phormia Terrae-novae) (CAS 129204-82-6)
- (4aR,6bS,8aR,9S,10S,11R,12aR,12bS,14bS)-(2S,3R,4S,5S,6R)-3-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl 10,11-dihydroxy-9-(hydroxymethyl)-2,2,6b,8a,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate (CAS 103444-92-4)
- Lesinurad Impurity 15 (CAS CATO-C4X-147815)
- Blonanserin Impurity 15 (CAS 132813-14-0)
- Phenylephrine Impurity 73 (CAS CATO-C4X-146773)
- 3-(chloromethyl)-2-(2-isopropylpyrazol-3-yl)pyridine;hydrochloride (CAS 1446321-95-4)
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- 3-((4-Chlorobenzyl)oxy)piperidine hydrochloride (CAS 1220033-10-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com