Rivastigmine Impurity 20 CAS CATO-C4X-138420
| CAS No. | CATO-C4X-138420 |
| Molecular Formula | C10H15NO2 |
| Molecular Weight | 181.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Rivastigmine Impurity 20 (CAS CATO-C4X-138420, C10H15NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Rivastigmine Impurity 20 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H15NO2 |
| Molecular Weight | 181.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Rivastigmine Standards
- Rivastigmine Impurity N1 (CAS 1369779-38-3)
- Rivastigmine Impurity 43 (CAS CATO-C4X-138443)
- Rivastigmine EP Impurity F (CAS 889443-69-0)
- Rivastigmine Impurity 15 (CAS 169772-44-5)
- Rivastigmine Impurity N13 (CAS 2454-35-5)
- Rivastigmine Impurity N4 (CAS 58114-05-9)
- Rivastigmine Impurity N3 (CAS 90271-37-7)
- Rivastigmine EP Impurity A (CAS 139306-10-8)
Recommended Standards
- Pioglitazone Impurity 24 (CAS 127676-18-0)
- Phenylephrine Impurity 36 (CAS CATO-C4X-146736)
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- Carvedilol Impurity 20 (CAS 72955-82-9)
- Betamethasone Impurity 120 (CAS 82536-56-9)
- Mosapride Impurity 14 (CAS CATO-C4X-104414)
- Chlorpheniramine Impurity 37 (CAS CATO-C4X-118837)
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