Nimodipine Impurity 49 CAS CATO-C4X-138549
| CAS No. | CATO-C4X-138549 |
| Molecular Formula | C13H12ClNO5 |
| Molecular Weight | 297.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nimodipine Impurity 49.
As a process- or degradation-related impurity, Nimodipine Impurity 49 (CAS CATO-C4X-138549, C13H12ClNO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Nimodipine Impurity 49 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12ClNO5 |
| Molecular Weight | 297.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Nimodipine Standards
- Nimodipine Impurity 2 (CAS 62760-01-4)
- Nimodipine Impurity N1 (CAS 62760-10-5)
- Nimodipine Impurity 38 (CAS CATO-C4X-138538)
- Nimodipine Impurity 45 (CAS CATO-C4X-138545)
- Nimodipine Impurity 46 (CAS CATO-C4X-138546)
- Nimodipine Impurity 54 (CAS CATO-C4X-138554)
- Nimodipine Impurity 44 (CAS CATO-C4X-138544)
- Nimodipine Impurity 55 (CAS CATO-C4X-138555)
Recommended Standards
- 5-(2-CHloro-5-(trifluoromethyl)phenyl)isoindoline (CAS 1206970-34-4)
- (2-Chloro-6-morpholin-4-yl-9H-purin-9-yl)acetic acid (CAS 1374408-06-6)
- 8-Chloro-2-(4-hydroxyphenyl)-4-oxo-4H-chromene-7-carbonitrile (CAS 2413193-57-2)
- 2-Chloro-9-methyl-6-morpholino-9H-purine-8-carboxylic acid (CAS 1439824-88-0)
- Topiroxostat impurity 72 (CAS CATO-C4X-105572)
- Erlotinib impurity 129 (CAS CATO-C4X-1069129)
- Cefmetazole Impurity 10 (CAS CATO-C4X-150710)
- 2-(3-(2,6-Dimethylpyridin-3-yl)-5-(phenanthren-9-yl)phenyl)-4,6-diphenyl-1,3,5-triazine (CAS 2100261-14-9)
- 1-(Prop-2-en-1-yl)cyclopentane-1-carboxylic acid (CAS 411238-08-9)
- 25966-39-6 A818112 N-[2-(2,4-dinitrophenyl)azo-5-[(2-hydroxy-3-methoxypropyl)amino]-4-methoxyphenyl]acetamide N-[2-[(2,4-dinitrophenyl)diazenyl]-4-methoxy-5-[(3-methoxy-2-oxidanyl-propyl)amino]phenyl]ethanamide (CAS 25966-39-6)
- 3-Chloro-6-(methylsulfonyl)pyridazine (CAS 7145-62-2)
- Glycine-13C2,15N (CAS 211057-02-2)
- (S)-2-amino-3-(3-chlorophenyl)propan-1-ol (CAS 938462-28-3)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
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