Budesonide Impurity 74 CAS CATO-C4X-138974
| CAS No. | CATO-C4X-138974 |
| Molecular Formula | C21H26O5 |
| Molecular Weight | 358.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Budesonide Impurity 74 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Budesonide Impurity 74 (CAS CATO-C4X-138974, C21H26O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Budesonide Impurity 74 (C21H26O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Budesonide Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H26O5 |
| Molecular Weight | 358.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Budesonide Standards
- Budesonide Impurity 15 (CAS CATO-C4X-138915)
- Budesonide Impurity 18 (CAS CATO-C4X-138918)
- Budesonide Impurity 20 (CAS CATO-C4X-138920)
- Budesonide Impurity 26 (CAS 77017-17-5)
- Budesonide Impurity 47 (CAS CATO-C4X-138947)
- Budesonide Impurity N2 (CAS 39672-76-9)
- Budesonide Impurity 58 (CAS CATO-C4X-138958)
- Budesonide Impurity 64 (CAS 69155-84-6)
Recommended Standards
- Beclomethasone dipropionate Impurity 31 (CAS CATO-C4X-147431)
- Formoterol EP Impurity C (CAS 1795135-61-3)
- Formoterol EP Impurity D (CAS 1795133-96-8)
- Formoterol EP Impurity E (CAS 1616967-26-0)
- Docetaxel Impurity 65 (CAS CATO-C4X-161965)
- Cefepime EP Impurity B (CAS CATO-C4X-11932)
- Ursodeoxycholic Acid EP Impurity I (CAS 130593-75-8)
- 1-(Methylamino)-3-(pyrrolidin-1-yl)propan-2-ol (CAS 756520-80-6)
- 2-(5-Chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)acetic acid (CAS 1007515-51-6)
- 7-Amino-4-methoxy-2,3-dihydro-1H-inden-1-one (CAS 121062-93-9)
- Lithium sulfate monohydrate (CAS 10102-25-7)
- (4-methoxy-2-methylpyrrolidin-2-yl)methanol (CAS 2059935-13-4)
- 2-Ethyl-3-methyl-1-(piperazin-1-yl)benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile (CAS 294651-63-1)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
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