Alfacalcidol Impurity 26 CAS CATO-C4X-139326
| CAS No. | CATO-C4X-139326 |
| Molecular Formula | C27H43ClO |
| Molecular Weight | 419.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Alfacalcidol Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Alfacalcidol Impurity 26 (CAS CATO-C4X-139326, C27H43ClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C27H43ClO, Alfacalcidol Impurity 26 contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 419.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C27H43ClO |
| Molecular Weight | 419.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Alfacalcidol Standards
- Alfacalcidol Impurity 24 (CAS CATO-C4X-139324)
- Alfacalcidol impurity 10 (CAS 174176-73-9)
- Alfacalcidol impurity 17 (CAS 2227309-93-3)
- Alfacalcidol-d7 (CAS 41294-56-8 (non-d))
- Alfacalcidol-d6 (CAS 1641940-94-4)
- Alfacalcidol (CAS 41294-56-8)
- Alfacalcidol EP Impurity A (CAS 65445-14-9)
- Alfacalcidol impurity 13 (CAS 58028-00-5)
Recommended Standards
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- Leucogen Impurity 10 (CAS CATO-C4X-288910)
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- Salbutamol Impurity 193 (CAS CATO-C4X-1176193)
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- 1-(5-Chlorospiro[indoline-3,4'-piperidin]-1-yl)ethanone (CAS 637362-19-7)
- Methyl (1R,2R,5R)-3-benzyl-2-(methoxymethyl)-3-azabicyclo[3.1.0]hexane-1-carboxylate (CAS 1868104-37-3)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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