N-Nitroso Metronidazole Impurity 32 CAS CATO-C4X-140532
| CAS No. | CATO-C4X-140532 |
| Molecular Formula | C3H2N4O3 |
| Molecular Weight | 142.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Nitroso Metronidazole Impurity 32.
N-Nitroso Metronidazole Impurity 32 (CAS CATO-C4X-140532) is a certified pharmaceutical impurity reference standard with the molecular formula C3H2N4O3 and a molecular weight of 142.07 g/mol.
The molecular framework of N-Nitroso Metronidazole Impurity 32 (C3H2N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H2N4O3 |
| Molecular Weight | 142.07 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-Nitroso-N-methylaniline-d5 (CAS 1821341-18-7)
- N-Nitroso-N-Ethyl Piperazine (CAS 65504-33-8)
- N-Nitroso Flecainide EP Impurity B (CAS CATO-C4X-25467)
- N-Nitroso-N-Allyl-3-Buten-1-Amine (CAS 54746-50-8)
- N-Nitroso-D-proline (CAS 42022-03-7)
- N-Nitroso-L-proline(Mixture of Isomers) (CAS 7519-36-0)
- N-Nitroso Nifedipine EP Impurity D (CAS CATO-C4X-141033)
- N-Nitroso Proline (CAS 2571-28-0)
Recommended Standards
- Fluconazole Impurity 74 (CAS CATO-C4X-101974)
- Metronidazole Impurity 35 (CAS CATO-C4X-140535)
- Croconic acid (CAS 488-86-8)
- 3,3,3-Trifluoro-N-hydroxypropanimidamide (CAS 1016726-53-6)
- Ziprasidone Impurity 13 (CAS CATO-C4X-124013)
- Peramivir Impurity 35 (CAS 251326-99-5)
- Minoxidil Impurity 25 (CAS 7148-63-2)
- (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate (CAS 137819-86-4)
- 2-{(S)-2-[(Cyclopropyl-methyl-amino)-methyl]-pyrrolidin-1-yl}-ethanol (CAS 1353985-96-2)
- 5-Bromo-4-(phenylamino)pyridine-3-sulfonic acid (CAS 1352508-05-4)
- 4-(ethylsulfanyl)benzonitrile (CAS 86047-01-0)
- 5-Nitrobenzo[c][1,2,5]oxadiazole (CAS 18772-11-7)
- rac-trans 3-Aminomethyl Nicotine (CAS 623579-03-3)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
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