Metoclopramide Impurity 110 CAS CATO-C4X-1415110
| CAS No. | CATO-C4X-1415110 |
| Molecular Formula | C28H40Cl2N6O4 |
| Molecular Weight | 595.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Metoclopramide Impurity 110 (CAS CATO-C4X-1415110, C28H40Cl2N6O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Metoclopramide Impurity 110 (C28H40Cl2N6O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H40Cl2N6O4 |
| Molecular Weight | 595.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Metoclopramide Standards
- Metoclopramide Impurity 108 (CAS CATO-C4X-1415108)
- Metoclopramide Impurity 123 (CAS CATO-C4X-1415123)
- Metoclopramide impurity 52 (CAS CATO-C4X-141552)
- Metoclopramide impurity 50 (CAS CATO-C4X-141550)
- Metoclopramide impurity 51 (CAS CATO-C4X-141551)
- Metoclopramide Impurity 35 (CAS CATO-C4X-141535)
- Metoclopramide impurity 60 (CAS 1242047-97-7)
- Metoclopramide Impurity 109 (CAS CATO-C4X-1415109)
Recommended Standards
- 2’,3’,5’-Tri-O-benzoyl Guanosine (CAS 66048-53-1)
- Quininesalicylate (CAS 750-90-3)
- 2-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-5-[(benzoyloxy)methyl]tetrahydrofuran-3,4-diyl dibenzoate (CAS 62374-25-8)
- Azilsartan Impurity 169 (CAS CATO-C4X-1096169)
- Stiripentol Iso Butyl Keto Impurity (CAS 56750-95-9)
- Prucalopride impurity 33 (CAS CATO-C4X-103833)
- Fulvestrant impurity 58 (CAS CATO-C4X-191758)
- 4-Methyl-10H-phenothiazine (CAS 7190-74-1)
- 2-Methyl-2-({[4-(methylsulfanyl)phenyl]methyl}amino)propan-1-ol (CAS 774556-25-1)
- 3-Fluoropropylamine hydrochloride 3-fluoro-propylamine hydrochloride 3-fluoropropan-1-amine hydrochloride 64068-31-1 (CAS 64068-31-1)
- [1,1'-Biphenyl]-4-carboximidamide (CAS 125772-44-3)
- 4,8-Dichloroquinoline-3-carbonitrile (CAS 1016867-23-4)
- N2-Acetamido-6-benzyloxypurine (CAS 92193-74-3)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
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