Metoclopramide impurity 74 CAS CATO-C4X-141574
| CAS No. | CATO-C4X-141574 |
| Molecular Formula | C28H43N6O4 |
| Molecular Weight | 527.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metoclopramide impurity 74.
Metoclopramide impurity 74 (CAS CATO-C4X-141574) is a certified pharmaceutical impurity reference standard with the molecular formula C28H43N6O4 and a molecular weight of 527.68 g/mol.
The molecular framework of Metoclopramide impurity 74 (C28H43N6O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Metoclopramide impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H43N6O4 |
| Molecular Weight | 527.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Metoclopramide Standards
- Metoclopramide Impurity 126 (CAS CATO-C4X-1415126)
- Metoclopramide Impurity 94 (CAS CATO-C4X-141594)
- Metoclopramide impurity 73 (CAS CATO-C4X-141573)
- Metoclopramide impurity 71 (CAS CATO-C4X-141571)
- Metoclopramide Impurity 124 (CAS CATO-C4X-1415124)
- Metoclopramide Impurity 109 (CAS CATO-C4X-1415109)
- Metoclopramide impurity 54 (CAS CATO-C4X-141554)
- Metoclopramide impurity 56 (CAS 1242048-03-8)
Recommended Standards
- N-Formyl-Met-Leu-Phe benzyl ester (CAS 70637-32-0)
- Ethyl 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoate (CAS 76812-02-7)
- ((2S)-2-((2S,3S)-3-Amino-2-hydroxy-N-methyldecanamido)-4-(methylsulfinyl)butanoyl)-L-tyrosine (CAS 1135249-50-1)
- 2-(2-((2-Aminoethyl)amino)ethyl)-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one (CAS 1005459-81-3)
- Tulobuterol Impurity 11 (CAS 14467-32-4)
- Urapidil Impurity 89 (CAS CATO-C4X-192489)
- Levonorgestrel EP Impurity J (CAS 1175109-63-3)
- 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-amine (CAS 1312020-01-1)
- Acridine Related Compound 8 (CAS 6818-07-1)
- 1,3-Di(pyrrolidin-1-yl)prop-2-ene-1-thione (CAS 15182-52-2)
- 1-(2-Chlorobenzyl)-1H-indol-3-yl imidothiocarbamate hydroiodide (CAS 1049785-15-0)
- 6-methyl-1,2,3,4-tetrahydroquinoxaline (CAS 6639-93-6)
- 2-(2-Methylpiperidin-1-yl)-5-nitroaniline (CAS 1465452-47-4)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com