Promethazine Impurity 19 CAS CATO-C4X-141819
| CAS No. | CATO-C4X-141819 |
| Molecular Formula | C17H20N2OS |
| Molecular Weight | 300.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Promethazine Impurity 19 (C17H20N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Promethazine Impurity 19 (CAS CATO-C4X-141819) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20N2OS and a molecular weight of 300.42 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H20N2OS |
| Molecular Weight | 300.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Promethazine Standards
- Promethazine sulfoxide HCl (CAS 5306-81-0)
- Promethazine Impurity 36 (CAS CATO-C4X-141836)
- Promethazine EP Impurity D (CAS 7640-51-9)
- Promethazine impurity 55 (CAS CATO-C4X-141855)
- Promethazine Impurity 64 (CAS CATO-C4X-141864)
- Promethazine Impurity 61 (CAS CATO-C4X-141861)
- Promethazine Impurity 62 (CAS CATO-C4X-141862)
- Promethazine Impurity 65 (CAS CATO-C4X-141865)
Recommended Standards
- N-Ethyl-4-(quinolin-2-yl)piperazine-1-carbothioamide (CAS 89007-50-1)
- N-[4-(Butan-2-yl)phenyl]-2-(pyridin-2-ylsulfanyl)acetamide (CAS 256955-15-4)
- Diisobutyl Nonanedioate (CAS 105-80-6)
- N-(4-Butylphenyl)-2-(pyridin-2-ylsulfanyl)acetamide (CAS 329080-05-9)
- Ensifentrine impurity 32 (CAS CATO-C4X-335332)
- Carbetocin Impurity 14 (CAS CATO-C4X-191114)
- Molnupiravir Impurity 13 (CAS CATO-C4X-249013)
- 2-(Ethylthio)-N-(4-methoxybenzo[d]thiazol-2-yl)benzamide (CAS 886915-34-0)
- (2E)-N-(4-Iodophenyl)-3-[4-(methylsulfanyl)phenyl]prop-2-enamide (CAS 329058-97-1)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(prop-2-yn-1-yl)-1H-pyrrole-2-sulfonamide (CAS 338407-37-7)
- 2-Cyano-n-[4-(3,4-dihydroxyphenyl)-1,3-thiazol-2-yl]acetamide (CAS 851169-22-7)
- N-tert-Butyl-3,5-dimethyl-1H-pyrazole-4-sulfonamide (CAS 1032038-96-2)
- 2-(3-Fluorophenyl)-1-(4-(methylthio)phenyl)ethan-1-one (CAS 301699-27-4)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
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