Dapoxetine Impurity 88 CAS CATO-C4X-143988
| CAS No. | CATO-C4X-143988 |
| Molecular Formula | C18H21ClO2 |
| Molecular Weight | 304.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dapoxetine Impurity 88.
As a process- or degradation-related impurity, Dapoxetine Impurity 88 (CAS CATO-C4X-143988, C18H21ClO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dapoxetine Impurity 88 (C18H21ClO2) contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 304.81 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H21ClO2 |
| Molecular Weight | 304.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Dapoxetine Standards
- Dapoxetine Impurity 92 (CAS CATO-C4X-143992)
- Dapoxetine Impurity 102 (CAS 119356-77-3)
- Dapoxetine Impurity 103 (CAS 1135682-44-8)
- Dapoxetine Impurity 29 (CAS CATO-C4X-143929)
- Dapoxetine Impurity 9 (CAS 119357-39-0)
- Dapoxetine RC 2 (CAS 1776071-89-6)
- Dapoxetine Impurity 32 (CAS CATO-C4X-143932)
- Dapoxetine Impurity 40 (CAS CATO-C4X-143940)
Recommended Standards
- N-((2-chloro-6-ethoxyquinolin-3-yl)methyl)cyclopentanamine (CAS 917746-04-4)
- 1-((5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl)-4-methylpiperazine (CAS 477714-03-7)
- 7-Chloro-4-(1-ethylpiperidin-4-yl)-3-methylisoquinolin-1(2H)-one (CAS 702709-38-4)
- 4-(4-Chlorophenyl)-5-(phenylsulfanyl)-1,2,3-thiadiazole (CAS 338408-15-4)
- Ornidazole Impurity 74 (CAS CATO-C4X-133174)
- Brivaracetam Impurity 178 (CAS CATO-C4X-2007178)
- Desloratadine Impurity 26 (CAS 153200-97-6)
- Ethyl 8-carbamoyl-4-methylene-1,4-dihydroimidazo[5,1-c][1,2,4]triazine-3-carboxylate (CAS 78695-90-6)
- 2-(tert-Butylamino)-4-isopropyl-1-methyl-1H-imidazol-5(4H)-one (CAS 787541-53-1)
- 3-Chloro-5-(2,3,4-trichlorophenyl)pyridin-4-amine (CAS 1361532-24-2)
- 2-((4-Chlorobut-2-yn-1-yl)oxy)tetrahydro-2H-pyran (CAS 67727-01-9)
- 3-Cyano-N-(dicyclopropylmethyl)benzamide (CAS 1050549-96-6)
- (1R)-1-(3-fluorofuran-2-yl)propan-1-amine (CAS 1391368-42-5)
- Neuropeptide S (human) (CAS 412938-67-1)
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