Iopamidol Impurity 26 CAS CATO-C4X-145026
| CAS No. | CATO-C4X-145026 |
| Molecular Formula | C18H24I3N3O8 |
| Molecular Weight | 791.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 791.11 g/mol gives Iopamidol Impurity 26 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Iopamidol Impurity 26 (CAS CATO-C4X-145026, C18H24I3N3O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Iopamidol Impurity 26 (C18H24I3N3O8) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Iopamidol Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24I3N3O8 |
| Molecular Weight | 791.11 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iopamidol Standards
- Iopamidol Impurity 50 (CAS CATO-C4X-145050)
- Iopamidol Impurity 56 (CAS CATO-C4X-145056)
- Iopamidol Impurity 47 (CAS CATO-C4X-145047)
- Iopamidol impurity 59 (CAS CATO-C4X-145059)
- Iopamidol EP Impurity G (CAS 1869069-72-6)
- (R)-Iopamidol (CAS 88375-91-1)
- Iopamidol (CAS 60166-93-0)
- Iopamidol Impurity 53 (CAS CATO-C4X-145053)
Recommended Standards
- Fluorotrichloroethylene (CAS 359-29-5)
- 1,2,3,4-Butanetetracarboxylic acid, 1,2,3,4-tetrakis(2,2,6,6-tetramethyl-4-piperidinyl) ester (CAS 64022-61-3)
- Iopromide (CAS 73334-07-3)
- Iopromide Impurity 24 (CAS 1651211-76-5)
- Ropinirole impurity 01 HCl (CAS 920755-10-8（free base）)
- Rasagiline impurity 60 (CAS CATO-C4X-191360)
- Urapidil Impurity 94 (CAS CATO-C4X-192494)
- H-Gly-Leu-Tyr-OH (CAS 4306-24-5)
- 4-(4-Propylpiperazin-1-yl)aniline (CAS 927998-85-4)
- (R)-1-(2-Methyl-5-nitro-3-(trifluoromethyl)phenyl)ethanamine (CAS 2230840-50-1)
- 3-Cyano-4-ethoxybenzoic acid (CAS 258273-32-4)
- 6-Ethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 100396-57-4)
- 5-Cyclopropoxy-4-sulfamoylnicotinamide (CAS 1243452-98-3)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
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