Mabuterol Impurity 8 CAS CATO-C4X-14548
| CAS No. | CATO-C4X-14548 |
| Molecular Formula | C15H15ClF3NO5 |
| Molecular Weight | 381.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Mabuterol Impurity 8 (C15H15ClF3NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Mabuterol Impurity 8 (CAS CATO-C4X-14548) is a certified pharmaceutical impurity reference standard with the molecular formula C15H15ClF3NO5 and a molecular weight of 381.73 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Mabuterol Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H15ClF3NO5 |
| Molecular Weight | 381.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Mabuterol Standards
- Mabuterol Impurity 3 (CAS CATO-C4X-14543)
- Mabuterol Impurity 11 (CAS CATO-C4X-145411)
- Mabuterol Impurity 9 (CAS CATO-C4X-14549)
- Mabuterol Impurity 12 (CAS CATO-C4X-145412)
- Mabuterol Impurity 4 (CAS CATO-C4X-14544)
- Mabuterol Impurity 7 (CAS CATO-C4X-14547)
- Mabuterol-d9 (CAS 1246819-58-8)
- Mabuterol Impurity 6 (CAS CATO-C4X-14546)
Recommended Standards
- 1,4-Dichloro-2,5-Bis(trichloromethyl)Benzene (CAS 2142-29-2)
- (1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl 3-(trifluoromethyl)benzoate (CAS 338419-27-5)
- [5-(4-Chlorophenyl)-1,2-oxazol-3-yl]methyl 3-(trifluoromethyl)benzoate (CAS 338777-03-0)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-1-yl)(4-methoxyphenyl)methanone (CAS 251096-69-2)
- Lusutrombopag Impurity 13 (CAS CATO-C4X-208413)
- Sulpiride Impurity 23 (CAS CATO-C4X-187623)
- Nilotinib Impurity 45 (CAS CATO-C4X-125645)
- 3,5-Dichloro-N-(3,4-dichlorophenyl)-N'-methylbenzimidamide (CAS 339010-01-4)
- [(3-Bromophenyl)methyl](propan-2-yl)amine (CAS 110079-41-9)
- 6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 97482-19-4)
- 2-(Carbamoylamino)-4-chlorobenzoic acid (CAS 214288-97-8)
- 1-(2-Chlorophenyl)-N-cyclohexyl-N-methylisoquinoline-3-carboxamide (CAS 89242-27-3)
- Manganese carbonyl(0) (CAS 10170-69-1)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
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