Busulfan Impurity 27 CAS CATO-C4X-145527
| CAS No. | CATO-C4X-145527 |
| Molecular Formula | C6H13ClO6S2 |
| Molecular Weight | 280.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Busulfan Impurity 27 .
Busulfan Impurity 27 (CAS CATO-C4X-145527) is a certified pharmaceutical impurity reference standard with the molecular formula C6H13ClO6S2 and a molecular weight of 280.75 g/mol.
The molecular framework of Busulfan Impurity 27 (C6H13ClO6S2) is characterized by a carbohydrate-derived structure, a sulfone group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Busulfan Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H13ClO6S2 |
| Molecular Weight | 280.75 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Busulfan Standards
- Busulfan impurity dimer (CAS CATO-C4X-145524)
- Busulfan Impurity 22 (CAS CATO-C4X-145522)
- Busulfan-d8 (CAS 116653-28-2)
- Busulfan (CAS 55-98-1)
- Busulfan impurity 26 (CAS CATO-C4X-145526)
- Busulfan Impurity 12 (CAS CATO-C4X-145512)
- Busulfan Impurity 21 (CAS CATO-C4X-145521)
- Busulfan Impurity 1 (CAS 1797106-48-9)
Recommended Standards
- Chlorphenamine Impurity 46 (CAS CATO-C4X-118846)
- 4-chloro-1-[2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)ethyl]-1H-pyrazol-3-amine (CAS 1174855-08-3)
- Palbociclib Impurity 199 (E-Isomer) (CAS CATO-C4X-1125199)
- 4-Chloro-5-methyl-1-((6,7,8,9-tetrahydro-5h-[1,2,4]triazolo[4,3-a]azepin-3-yl)methyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1174886-12-4)
- Formoterol impurity 116 (CAS CATO-C4X-1525116)
- Loratadine Impurity 97 (CAS CATO-C4X-142697)
- Empagliflozin impurity 316 (CAS CATO-C4X-1065316)
- (E)-4-(3,4-Dihydroxystyryl)-2-oxo-2H-pyran-6-carboxylic acid (CAS 180031-58-7)
- 2,3-Dihydrobenzofuran-4-carbonitrile (CAS 76093-75-9)
- 4-Cyano-2-(difluoromethyl)-5-methoxypyridine-3-sulfonyl chloride (CAS 1804732-40-8)
- 2,5-Dibromo-1,3-dichlorobenzene (CAS 19393-97-6)
- 5-Nitro-3,4-dihydropyrimidin-2(1H)-one (CAS 385437-61-6)
- 5-(Dibromomethyl)-2-(2-fluorophenyl)benzo[d]oxazole (CAS 1706454-01-4)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com