Rifampicin impurity 11 CAS CATO-C4X-145611
| CAS No. | CATO-C4X-145611 |
| Molecular Formula | C45H61N5O10 |
| Molecular Weight | 831.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Rifampicin impurity 11 (CAS CATO-C4X-145611, C45H61N5O10) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Rifampicin impurity 11 (C45H61N5O10) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C45H61N5O10 |
| Molecular Weight | 831.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Rifampicin Standards
Recommended Standards
- Cefepime Impurity 31 (CAS CATO-C4X-119331)
- H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2 (CAS 167875-35-6)
- Eptifibatide Acetate (CAS 188627-80-7)
- Cefmetazole Impurity 67 (CAS CATO-C4X-150767)
- Amoxicillin Impurity 41 (CAS CATO-C4X-114841)
- Acetylcysteine Impurity 47 (CAS 74401-71-1)
- Ropivacaine Impurity 24 (CAS 36588-46-2)
- Seselin (CAS 523-59-1)
- (E)-N'-(3-(4-chlorophenyl)acryloyl)benzohydrazide (CAS 1572040-08-4)
- Pirarubicin impurity 5 (CAS CATO-C4X-24685)
- 5,5-Dimethyl-8-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (CAS 166977-95-3)
- 4-(4-Acetamidophenyl)-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1356543-59-3)
- 2-Bromo-3-(methylsulfonyl)pyridine (CAS 1209459-11-9)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com