Norfloxacin Impurity 20 CAS CATO-C4X-146820
| CAS No. | CATO-C4X-146820 |
| Molecular Formula | C19H24FN3O5 |
| Molecular Weight | 393.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Norfloxacin Impurity 20.
Norfloxacin Impurity 20 (CAS CATO-C4X-146820) is a certified pharmaceutical impurity reference standard with the molecular formula C19H24FN3O5 and a molecular weight of 393.41 g/mol.
The molecular framework of Norfloxacin Impurity 20 (C19H24FN3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Norfloxacin Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H24FN3O5 |
| Molecular Weight | 393.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Norfloxacin Standards
- Norfloxacin Impurity 62 (CAS CATO-C4X-146862)
- Norfloxacin EP Impurity H (CAS 105440-01-5)
- Norfloxacin Impurity 21 (CAS 103240-27-3)
- Norfloxacin Impurity 41 (CAS CATO-C4X-146841)
- Norfloxacin Impurity 51 (CAS CATO-C4X-146851)
- Norfloxacin Impurity 56 (CAS CATO-C4X-146856)
- Norfloxacin Impurity 54 (CAS CATO-C4X-146854)
- Norfloxacin Impurity 55 (CAS CATO-C4X-146855)
Recommended Standards
- Methyl 3-(1,3-benzodioxol-5-yl)-3-{[(4-methoxyphenyl)sulfonyl]amino}propanoate (CAS 866144-34-5)
- 7-Fluoro-3,4-dihydro-4-[(5-isoquinolinyloxy)acetyl]-1,3,3-trimethyl-2(1H)-quinoxalinone (CAS 878292-27-4)
- Cefprozil Impurity 12 (CAS CATO-C4X-149212)
- 4-Methyl-5-[3-(2-pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl]-4H-1,2,4-triazole-3-thiol (CAS 551921-22-3)
- Moxifloxacin impurity 198 (CAS CATO-C4X-1074198)
- Felodipine Impurity 14 (CAS 95306-64-2)
- Oseltamivir Impurity 96 (CAS CATO-C4X-172096)
- 2-(Piperazin-1-yl)acetic acid hydrochloride (CAS 1222197-25-2)
- Methyl 8-fluoroisoquinoline-3-carboxylate (CAS 794515-94-9)
- 5-(Chloromethyl)-1H-1,2,3-triazole hydrochloride (CAS 1803601-21-9)
- Ethyl furan-2-carboxylate (CAS 614-99-3)
- 2-Amino-1-(4-methoxybenzyl)-4,5,6,7-tetrahydro-1H-indole-3-carbonitrile (CAS 113772-12-6)
- 3-(1-(1H-Benzo[d][1,2,3]triazol-1-yl)propyl)-1,3-thiazinane-2-thione (CAS 849414-25-1)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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