Ketoprofen Impurity 66 CAS CATO-C4X-147166
| CAS No. | CATO-C4X-147166 |
| Molecular Formula | C22H22O9 |
| Molecular Weight | 430.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Ketoprofen Impurity 66 (CAS CATO-C4X-147166), a pharmacopoeial impurity reference standard (molecular formula C22H22O9, MW 430.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Ketoprofen Impurity 66 (C22H22O9) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22O9 |
| Molecular Weight | 430.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ketoprofen Standards
- (R)-Ketoprofen β-D-glucuronide (CAS 140148-25-0)
- (S)-Ketoprofen β-D-glucuronide (CAS 140148-26-1)
- rac-Ketoprofen acyl-beta-D-glucuronide (mixture of isomers) (CAS 76690-94-3)
- Ketoprofen Impurity 56 (CAS 157740-17-5)
- Ketoprofen Impurity 57 (CAS CATO-C4X-147157)
- Ketoprofen Impurity 50 (CAS 157740-16-4)
- Ketoprofen Impurity 83 (CAS CATO-C4X-147183)
- Ketoprofen Impurity 84 (CAS CATO-C4X-147184)
Recommended Standards
- 914111-18-5 Polygalatenoside A (CAS 914111-18-5)
- Ononin (CAS 486-62-4)
- Flavone, 5-hydroxy-3,3',4',6,7-pentamethoxy-, acetate (CAS 95135-98-1)
- (R)-10-Monohydroxy-10,11-dihydro Carbamazepine O-β-D-Glucuronide Sodium Salt (CAS 104746-01-2)
- Cyclophosphamide impurity 41 (CAS CATO-C4X-230641)
- Ceftolozane Impurity 24 (CAS CATO-C4X-240624)
- Celecoxib Impurity 30 (CAS 2356153-95-0)
- 4-(N-Butyl-N-methylsulfamoyl)-N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)benzamide (CAS 850935-79-4)
- (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(2H-1,2,3,4-tetrazol-5-yl)propanoic acid (CAS 954147-35-4)
- 3-(3-Methyl-1H-1,2,4-triazol-1-yl)adamantane-1-carboxylic acid (CAS 878420-70-3)
- 8-Bromo-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-amine (CAS 33631-96-8)
- Methyl 2-(piperidin-4-yl)benzoate hydrochloride (CAS 170838-23-0)
- Dihydrocodeine impurity 1 (CAS 23185-97-9)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
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