Norepinephrine impurity 86 TFA salt CAS CATO-C4X-151486
| CAS No. | CATO-C4X-151486 |
| Molecular Formula | C16H15NO6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Norepinephrine impurity 86 TFA salt (CAS CATO-C4X-151486, C16H15NO6C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Norepinephrine impurity 86 TFA salt (C16H15NO6C2HF3O2) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15NO6 C2HF3O2 |
| Molecular Weight | 431.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 50 (CAS 100622-09-1)
- Norepinephrine Impurity 103 (CAS 102743-86-2)
- Norepinephrine EP Impurity F (CAS 103-49-1)
- Norepinephrine Impurity 107 (CAS 112346-92-6)
- Norepinephrine Impurity 28 (CAS 117883-03-1)
- Norepinephrine Impurity 22 (CAS 1197-09-7)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Norepinephrine Impurity 161 (CAS 1215-29-8（free acid）)
Recommended Standards
- Dienogest Impurity 19 (CAS 7291-52-3)
- Propranolol Impurity 9 (CAS 4662-18-4)
- Ketotifen Impurity 30 (CAS CATO-C4X-204630)
- Dequalinium EP Impurity A (CAS 6628-04-2)
- 5-Methyl-3,3'-bipyridine (CAS 78210-82-9)
- RIFAPENTINE (CAS 1279038-35-5)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618427-30-8)
- 4-Cyclopropyl-2-(4-methylpiperidin-1-yl)pyrimidine-5-carboxylic acid (CAS 1707399-69-6)
- 2,5-Difluoro-4-methylbenzodifluoride (CAS 1803735-01-4)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com