Norepinephrine Impurity 94 HCl CAS CATO-C4X-151494
| CAS No. | CATO-C4X-151494 |
| Molecular Formula | C11H15NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Norepinephrine Impurity 94 HCl (CAS CATO-C4X-151494, C11H15NO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Norepinephrine Impurity 94 HCl (C11H15NO3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Norepinephrine Impurity 94 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15NO3 HCl |
| Molecular Weight | 245.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 50 (CAS 100622-09-1)
- Norepinephrine Impurity 103 (CAS 102743-86-2)
- Norepinephrine EP Impurity F (CAS 103-49-1)
- Norepinephrine Impurity 107 (CAS 112346-92-6)
- Norepinephrine Impurity 28 (CAS 117883-03-1)
- Norepinephrine Impurity 22 (CAS 1197-09-7)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Norepinephrine Impurity 161 (CAS 1215-29-8（free acid）)
Recommended Standards
- Carbazochrome impurity 45 (CAS CATO-C4X-229145)
- Chlorpheniramine Impurity 35 (CAS CATO-C4X-118835)
- Vinpocetine Impurity 33 (CAS 4752-37-8)
- Ethyl 2-amino-4-(trifluoromethyl)thiazole-5-carboxylate hydrochloride (CAS 31119-10-5)
- 4-Hydroxy-2,6-dimethylpyridine-3-carbonitrile (CAS 30145-81-4)
- Sodium 3-sulphonatopropyl acrylate (CAS 15717-25-6)
- N-(4-aminophenyl)-2-(4-methoxyphenyl)acetamide (CAS 1016764-21-8)
- 4-Chloro-2-(difluoromethyl)-5-(trifluoromethyl)nicotinonitrile (CAS 1804464-97-8)
- [2,3'-Bipyridine]-5'-carboxamide (CAS 1346686-51-8)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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